There has been considerable research into the active ingredient (Stabilised Chlorine Dioxide) in oral hygiene products. The following abstracts are from research papers published in Dental Journals or presented at IADR and AADR meetings, ascertaining to the efficacy of the active ingredient Stabilised Chlorine Dioxide present in the UltraDEX oral care range (formerly known as RetarDEX/ RetarDENT).
Management of Periodontitis with Oral Care-Products
Conrad W Chapek, Omer K Reed, Perry A Ratcliff, DDS, Emeritus Professor University of California at San Francisco School of Dentistry. USA
The Relationship between Oral Malodour, Gingivitis and Periodontitis. A Review.
Perry R Ratcliff and Paul W Johnson, Division of Periodontology, Department of Stomatology, School of Dentistry, university of California, San Francisco, CA
Odour Reduction Potential of a Chlorine Dioxide containing Mouthrinse.
J Frascella, DMD R Gilbert, PhD P Fernandez, RDH, TKL Research Inc. New Jersey
- Reduction of Volatile Sulphur Compounds (VSCs) after using RetarDEX Oral Rinse
Measurements taken using a Halimeter instrument. Conducted by Analyse Inc; Tempe, Arizona USA March 1992
- Effects of Chlorine Dioxide mouth rinse on oral Streptococci, Lactobacilli and Candida Albican.
D Gill, S Wakefield, A Kersey, K Seymour and E Lynch. The London Hospital Medical College, London.
- Anti-microbial capacity of a Chlorine Dioxide based toothpaste
P Ratcliff and V Bolin. Northern Arizona University, Flagstaff, Arizona USA.Presented at IADR meeting 1993
- Multicomponent Spectroscopic investigations of Salivary Antioxidant Consumption by Oral Rinse preparation containing the stable Free Radical Species Chlorine Dioxide (ClO2 )
E Lynch, A Sheerin, A W D Claxson, M D Atherton, C J Rhodes, C J L Silwood, D P Naughton and M Grootveld. Dept of Conservative Dentistry & Inflammation Research Group, St Bartholomews & the Royal London Hospitals Schools of Medicine & Dentistry, London. Department of Chemistry, Queen Mary and Westfield College, University of London, London.
- Evaluation of Oral Health Care Products to Alleviate Oral Malodour
M Grootveld, C Silwood and E Lynch Inflammation Research Group and Department of Conservative Dentistry, St Batholomew’s and the Royal London School of Medicine and Dentistry, London. Presented to an IADR 1997 Orlando, USA.
- Effect on oral malodour of Chlorine Dioxide (ClO2) assessed by a Hedonic panel
Frascella J., Gilbert R., Fernandex P.,Gordon P. TKL research Inc. Paramus, New Jersey. USA Presented to an IADR meeting 1998 USA
- Dental Abrasion of Dentifrices
Data courtesy of ADA Conducted by Oral Health Research Institute, Indianapolis, Indiana, USA July 14th 1992
- Germicidal effect of Povidone-Iodide and Chlorine Dioxide ClO2 on Dental Pathogens
PA Ratcliff, V Bolin, Northern Arizona University, Flagstaff, Arizona, USA. Presented to an AADR meeting 1992
- Chlorine Dioxide ClO2 /Phosphate Germicide vs. Actinobacillus actinomycetemcomitans (Aa) and Prophromonas (P). (Bacteroides) Gingivalis
P A Ratcliff, V Bolin, Northern Arizona University, Flagstaff, Arizona. Research abstract 669 presented at the AADR Annual meeting in 1992.
- Use of an oxidising agent to destroy amino acids to prevent their use as building blocks for protein
P.A. Ratcliff. Presented to the IADR meeting Nice, France 1998
- Reduction of bleeding on Probing with Oral-Care Products
Conrad W . Chapek DDS, Illinois, Omer K Reed DDS, Pheonix Arizona, Professor Perry Ratcliffe, University of California School of Dentistry Compendium Vo.16 No2, 1995
- Efficacy of a chlorine dioxide – containing mouth rinse in oral malodour.
Franceella J, DMD. Senior Director Oral health Research, Gilbert R D. Senior Director Biostatistics, Fernandez P, Clinical Co ordinator Oral health Research, Hendler J, Associate Director, TKl Research Inc. Paramus, New Jersey. Compendium March 2000
- Effects of stabilised Chlorine Dioxide and Chlorhexidene Mouthrinses in vitro on cells involved in periodontal healing
M. Robert Wirthlin,DDS, Brand J. AHN, DDS Belma Enriquez, BS, M. Zamirul Hussain, PhD. Periodontal abstract Volume 54 Number 3 2006
- Long-term diurnal investigation of the capacity of an oral healthcare product to neutralise Oral Malodour
A Report Prepared by Professor Martin Grootveld BSc PhD MIBMS CBiol FSB FRSC MK Biomedical and Clinical Research Ltd, Atherton, Manchester M46 0DR Awaiting Publication
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